Protein Kinase Classification: CMGC CDK※ CDK family introduction CDK (Cyclin-dependent kinase) belong to CMGC family. CDKs are ser/thr protein kinases that play an important in regulation of a number of cellular processes in eukaryotes. CDKs are also characterized by its feature that they require an activation subunit called cyclin (1).
Reference
1. Casteel, D.E., Zhang, T., Zhuang, S. and Pilz, R.B. (2008) cGMP-dependent protein kinase anchoring by IRAG regulates its nuclear translocation and transcriptional activity. Cell Signal, 20, 1392-1399. PMID: 18450420
CMGC CDK in eukaryotes:
1. Casteel, D.E., Zhang, T., Zhuang, S. and Pilz, R.B. (2008) cGMP-dependent protein kinase anchoring by IRAG regulates its nuclear translocation and transcriptional activity. Cell Signal, 20, 1392-1399. PMID: 18450420
CMGC CDK in eukaryotes: