Kinase Classification: PPP SLP※ SLP family introduction SLP is a unique family of PPP phosphatases, which is highly conserved among all plants and members also can be found in fungi and bacteria. Arabidopsis thaliana contains two SLP phosphatases: SLP1 and SLP2. SLP1 and SLP2 localize to different cellular compartments, with SLP1 found in chloroplastic and SLP2 found in cytosolic. SLP are metal cation dependent phosphatase and show preferences to Mn2+ and Fe3+. In addition, SLP members contain core signature motifs of PPP family phosphatases and act as ser/thr protein phosphatase (1).
Reference
1. Uhrig, R.G. and Moorhead, G.B. (2011) Two ancient bacterial-like PPP family phosphatases from Arabidopsis are highly conserved plant proteins that possess unique properties. Plant Physiol, 157, 1778-1792. PMID: 21976480
PPP SLP in eukaryotes:
1. Uhrig, R.G. and Moorhead, G.B. (2011) Two ancient bacterial-like PPP family phosphatases from Arabidopsis are highly conserved plant proteins that possess unique properties. Plant Physiol, 157, 1778-1792. PMID: 21976480
PPP SLP in eukaryotes:
| Arabidopsis lyrata (2) | Arabidopsis thaliana (2) | Brachypodium distachyon (2) |
| Brassica rapa (2) | Chlamydomonas reinhardtii (3) | Cyanidioschyzon merolae (1) |
| Glycine max (3) | Musa acuminata (2) | Oryza brachyantha (1) |
| Oryza glaberrima (2) | Oryza indica (1) | Oryza sativa (2) |
| Physcomitrella patens (3) | Populus trichocarpa (2) | Schizosaccharomyces pombe (1) |
| Selaginella moellendorffii (4) | Setaria italica (2) | Solanum lycopersicum (2) |
| Solanum tuberosum (1) | Sorghum bicolor (2) | Vitis vinifera (2) |
| Zea mays (4) |