※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway, which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylate ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase

  Reviewed (3)  or Unreviewed (0) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-SAC-00062	YNR047W	FPK1; YNR047W; N3449
2		EKS-SAC-00061	YCR091W	FPK2; KIN82; YCR1153, YCR91W; YCR091W
3		EKS-SAC-00060	YBR028C	YPK3; YBR0312; YBR028C