※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (8) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-PEM-00256	ENSPMAG00000003756	MAPK8 (2 of 2)
2		EKS-PEM-00258	ENSPMAG00000003042	MAPK4
3		EKS-PEM-00259	ENSPMAG00000001908	MAPK14
4		EKS-PEM-00255	ENSPMAG00000000656	MAPK8 (1 of 2)
5		EKS-PEM-00252	ENSPMAG00000009252	MAPK3
6		EKS-PEM-00257	ENSPMAG00000009404	MAPK15
7		EKS-PEM-00253	ENSPMAG00000008420	MAPK11
8		EKS-PEM-00254	ENSPMAG00000008402	MAPK13