Loxodonta africana      PPP      PP2A

※ PP2A family introduction

    PP2A, a family of PPP, is ubiquitously expressed in all eukaryotes. Three subunits compose this phosphatase holoenzyme, among which, subunit A is a 60-65 kDa structural component, B is a regulatory subunit and C is a 36-38 kDa catalytic subunit. The substrate specificity, spatial and temporal functions of PP2A is determined by regulatory subunit B. PP2A are involved in a lot of cellular processes such as cell cycle regulation, cell morphology and development. In addition, PP2A plays a critical role in regulation of specific signal transduction cascades (1).

Reference
1. Basu, S. (2011) PP2A in the regulation of cell motility and invasion. Curr Protein Pept Sci, 12, 3-11. PMID: 21190527


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusEKPD IDGene IDGene Name
1
EPS-LOA-00072
ENSLAFG00000027799
PPP2CB
2
EPS-LOA-00070
ENSLAFG00000029627
LOC100676230
3
EPS-LOA-00069
ENSLAFG00000016840
PPP2CA
4
EPS-LOA-00071
ENSLAFG00000029954