※ PP2B family introduction

    PP3, also known as Calcineurin (PP2B), is a Ca(2+)- and calmodulin-dependent Serine/Threonine protein phosphatase. PP2B shares a highly conserved catalytic subunit and heterodimeric quaternary structure from yeast to mammals. PP2B plays a important role in cellular processes and Ca(2+)-dependent signal transduction pathways, such as neurodevelopment, immune response, cardiac hypertrophy, signal transduction and muscle development (1).

Reference
1. Shi, Y. (2009) Serine/threonine phosphatases: mechanism through structure. Cell, 139, 468-484. PMID: 19879837

  Reviewed (2)  or Unreviewed (0) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EPS-MUM-00134	ENSMUSG00000022092	Ppp3cc; Calnc
2		EPS-MUM-00133	ENSMUSG00000028161	Ppp3ca; Calna