Homo sapiens      PTPLA      PTPLA

※ PTPLA family introduction

    PTPLA, Protein tyrosine phosphatase-like protein, contains protein tyrosine phosphatase-like proteins. Classical PTP is characterized by its signure motif CXXXXXR, however, the Arg to Pro(R/P) variation is found at active site in PTPLA. And PTPLA have been thought to play an important role in development, differentiation, and maintenance of a number of tissue types (1).

Reference
1. Uwanogho, D.A., Hardcastle, Z., Balogh, P., Mirza, G., Thornburg, K.L., Ragoussis, J. and Sharpe, P.T. (1999) Molecular cloning, chromosomal mapping, and developmental expression of a novel protein tyrosine phosphatase-like gene. Genomics, 62, 406-416. PMID: 10644438


There are 4 genes.  Reviewed (4 or Unreviewed (0

No.StatusEKPD IDGene IDGene Name
1
EPS-HOS-00111
ENSG00000188921
HACD4; PTPLAD2
2
EPS-HOS-00108
ENSG00000165996
PTPLA; HACD1
3
EPS-HOS-00109
ENSG00000206527
PTPLB; HACD2
4
EPS-HOS-00110
ENSG00000074696
BIND1, HACD3; PTPLAD1