Gasterosteus aculeatus      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusEKPD IDGene IDGene Name
1
EKS-GAA-00480
ENSGACG00000002188
YSK4; MAP3K19
2
EKS-GAA-00476
ENSGACG00000015579
MAP3K2
3
EKS-GAA-00479
ENSGACG00000003515
4
EKS-GAA-00475
ENSGACG00000007264
MAP3K5
5
EKS-GAA-00477
ENSGACG00000013722
MAP3K6
6
EKS-GAA-00478
ENSGACG00000005813
MAP3K4
7
EKS-GAA-00473
ENSGACG00000009795
MAP3K3
8
EKS-GAA-00474
ENSGACG00000005435
MAP3K15