Saccharomyces cerevisiae      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 5 genes.  Reviewed (5 or Unreviewed (0

No.StatusEKPD IDGene IDGene Name
1
EKS-SAC-00002
YNR031C
SSK2; YNR031C; N3276
2
EKS-SAC-00004
YJL095W
BCK1; J0906; LAS3, SLK1, SSP31; YJL095W
3
EKS-SAC-00003
YCR073C
YCR73C; YCR073C; SSK22
4
EKS-SAC-00001
YLR362W
STE11; YLR362W; L8039.10
5
EKS-SAC-00005
YAR019C
YAR019C; CDC15