Takifugu rubripes      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusEKPD IDGene IDGene Name
1
EKS-TAR-00495
ENSTRUG00000006321
MAP3K15
2
EKS-TAR-00496
ENSTRUG00000001070
MAP3K5
3
EKS-TAR-00494
ENSTRUG00000000166
MAP3K2
4
EKS-TAR-00499
ENSTRUG00000016338
MAP3K4
5
EKS-TAR-00497
ENSTRUG00000010218
MAP3K6
6
EKS-TAR-00493
ENSTRUG00000010417
MAP3K3
7
EKS-TAR-00498
ENSTRUG00000017481