Xenopus tropicalis      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family

There are 5 genes.  Reviewed (0)  or Unreviewed (5) 

No.StatusEKPD IDGene IDGene Name
1
EKS-XET-00503
ENSXETG00000018442
map3k3
2
EKS-XET-00501
ENSXETG00000006210
map3k15
3
EKS-XET-00502
ENSXETG00000002476
map3k5
4
EKS-XET-00499
ENSXETG00000000471
map3k2
5
EKS-XET-00500
ENSXETG00000008257
map3k3; XB-GENE-986927