※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway, which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylate ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase

  Reviewed (2)  or Unreviewed (2) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-CAE-00125	C54G4.1	C54G4.1; rskn-2
2		EKS-CAE-00126	R04A9.7	CELE_R04A9.7, R04A9.7; R04A9.7
3		EKS-CAE-00123	T01H8.1	T01H8.1; rskn-1
4		EKS-CAE-00124	Y47D3A.16	rsks-1