※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway, which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylate ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase

  Reviewed (0)  or Unreviewed (4) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-ORL-00181	ENSORLG00000012636	RPS6KB1 (2 of 2)
2		EKS-ORL-00179	ENSORLG00000012295	RPS6KB1 (1 of 2)
3		EKS-ORL-00178	ENSORLG00000009979	RPS6KA2
4		EKS-ORL-00180	ENSORLG00000002272	RPS6KB2