※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway, which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylate ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase

  Reviewed (1)  or Unreviewed (2) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-RAN-00152	ENSRNOG00000003919	Rps6kb1
2		EKS-RAN-00153	ENSRNOG00000021689	rCG_47735; Rps6kb2
3		EKS-RAN-00154	ENSRNOG00000004362	Rps6ka5