※ ABC1 family introduction

    ABC1 kinases are family of aarF domain-containing protein kinases which belong to atypical kinase group. Five members have been identified in human genome, known as ADCK1-ADCK5. ABC1 kinases contain the conserved protein kinase motifs which is responsible for the ATP binding and phosphotransfer reaction. However, as the overall sequence is distinct with ePK domain and lack of several usual kinase motifs, they are classified into "Atypical" kinase group (1).

Reference
1. Lagier-Tourenne, C., Tazir, M., Lopez, L.C., Quinzii, C.M., Assoum, M., Drouot, N., Busso, C., Makri, S., Ali-Pacha, L., Benhassine, T. et al. (2008) ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet, 82, 661-672. PMID: 18319074

  Reviewed (4)  or Unreviewed (1) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-MUM-00135	ENSMUSG00000021044	Adck1
2		EKS-MUM-00139	ENSMUSG00000046947	Adck2
3		EKS-MUM-00136	ENSMUSG00000026489	Adck3; Cabc1
4		EKS-MUM-00138	ENSMUSG00000022550	Adck5
5		EKS-MUM-00137	ENSMUSG00000003762	Adck4