※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (14) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-FEC-00438	ENSFCAG00000011912	MAPK11
2		EKS-FEC-00450	ENSFCAG00000011911	MAPK12
3		EKS-FEC-00443	ENSFCAG00000003342	MAPK8
4		EKS-FEC-00439	ENSFCAG00000023435	MAPK1
5		EKS-FEC-00449	ENSFCAG00000012154	MAPK4
6		EKS-FEC-00446	ENSFCAG00000007328	NLK
7		EKS-FEC-00448	ENSFCAG00000012570	MAPK6
8		EKS-FEC-00442	ENSFCAG00000025302	MAPK9
9		EKS-FEC-00441	ENSFCAG00000002234	MAPK10
10		EKS-FEC-00440	ENSFCAG00000001747	MAPK13
11		EKS-FEC-00444	ENSFCAG00000008844	MAPK7
12		EKS-FEC-00445	ENSFCAG00000014173	MAPK3
13		EKS-FEC-00437	ENSFCAG00000027782	MAPK14
14		EKS-FEC-00447	ENSFCAG00000027096	MAPK15