※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (13) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-LOA-00477	ENSLAFG00000016594	MAPK12
2		EKS-LOA-00476	ENSLAFG00000013022	MAPK4
3		EKS-LOA-00471	ENSLAFG00000017904	MAPK3
4		EKS-LOA-00466	ENSLAFG00000005132	MAPK14
5		EKS-LOA-00467	ENSLAFG00000005137	MAPK13
6		EKS-LOA-00470	ENSLAFG00000030236	MAPK8
7		EKS-LOA-00469	ENSLAFG00000012079	MAPK10
8		EKS-LOA-00478	ENSLAFG00000030490
9		EKS-LOA-00474	ENSLAFG00000013797	NLK
10		EKS-LOA-00475	ENSLAFG00000013900	MAPK6
11		EKS-LOA-00473	ENSLAFG00000010050	MAPK1
12		EKS-LOA-00472	ENSLAFG00000010277	MAPK7
13		EKS-LOA-00468	ENSLAFG00000014532	MAPK9