※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (13) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-MYL-00455	ENSMLUG00000014822	MAPK10
2		EKS-MYL-00458	ENSMLUG00000002164	MAPK12
3		EKS-MYL-00457	ENSMLUG00000011284	MAPK3
4		EKS-MYL-00460	ENSMLUG00000005952
5		EKS-MYL-00453	ENSMLUG00000005967	MAPK14
6		EKS-MYL-00454	ENSMLUG00000005924	MAPK9
7		EKS-MYL-00463	ENSMLUG00000000823	MAPK6
8		EKS-MYL-00461	ENSMLUG00000023153
9		EKS-MYL-00465	ENSMLUG00000024504	MAPK13
10		EKS-MYL-00462	ENSMLUG00000008681	NLK
11		EKS-MYL-00459	ENSMLUG00000008040	MAPK7
12		EKS-MYL-00464	ENSMLUG00000014569	MAPK4
13		EKS-MYL-00456	ENSMLUG00000014533	MAPK8