※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (12) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-ORA-00408	ENSOANG00000005892
2		EKS-ORA-00400	ENSOANG00000009986	MAPK13
3		EKS-ORA-00403	ENSOANG00000013418	NLK
4		EKS-ORA-00410	ENSOANG00000001768
5		EKS-ORA-00401	ENSOANG00000006227	MAPK10
6		EKS-ORA-00411	ENSOANG00000030386
7		EKS-ORA-00409	ENSOANG00000014961	MAPK15
8		EKS-ORA-00405	ENSOANG00000012095	MAPK8
9		EKS-ORA-00407	ENSOANG00000011529	ox_plat1_42208; LOC100078485
10		EKS-ORA-00406	ENSOANG00000011226	MAPK11
11		EKS-ORA-00402	ENSOANG00000010228	MAPK9
12		EKS-ORA-00404	ENSOANG00000008123	MAPK4