※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (9) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-SUS-00409	ENSSSCG00000010380	JNK1; MAPK8
2		EKS-SUS-00410	ENSSSCG00000010081	MAPK1; ERK2
3		EKS-SUS-00411	ENSSSCG00000004624	MAPK6
4		EKS-SUS-00412	ENSSSCG00000004520	MAPK4
5		EKS-SUS-00407	ENSSSCG00000009228	MAPK10
6		EKS-SUS-00408	ENSSSCG00000014010	MAPK9
7		EKS-SUS-00414	ENSSSCG00000024187	LOC100738058; MAPK8
8		EKS-SUS-00413	ENSSSCG00000017756
9		EKS-SUS-00406	ENSSSCG00000001556	MAPK14