※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (15) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-TAG-00535	ENSTGUG00000016564
2		EKS-TAG-00528	ENSTGUG00000004046	MAPK12
3		EKS-TAG-00524	ENSTGUG00000004078	MAPK11
4		EKS-TAG-00530	ENSTGUG00000008692	NLK
5		EKS-TAG-00529	ENSTGUG00000008602	MAPK1
6		EKS-TAG-00527	ENSTGUG00000008103	MAPK8
7		EKS-TAG-00533	ENSTGUG00000015060
8		EKS-TAG-00532	ENSTGUG00000015065
9		EKS-TAG-00534	ENSTGUG00000015839
10		EKS-TAG-00525	ENSTGUG00000002750	MAPK10
11		EKS-TAG-00531	ENSTGUG00000006789	MAPK6
12		EKS-TAG-00522	ENSTGUG00000001633	MAPK14
13		EKS-TAG-00523	ENSTGUG00000001624	MAPK13
14		EKS-TAG-00526	ENSTGUG00000001138	MAPK9
15		EKS-TAG-00536	ENSTGUG00000012787