Homo sapiens      PPP      PP2B

※ PP2B family introduction

    PP3, also known as Calcineurin (PP2B), is a Ca(2+)- and calmodulin-dependent Serine/Threonine protein phosphatase. PP2B shares a highly conserved catalytic subunit and heterodimeric quaternary structure from yeast to mammals. PP2B plays a important role in cellular processes and Ca(2+)-dependent signal transduction pathways, such as neurodevelopment, immune response, cardiac hypertrophy, signal transduction and muscle development (1).

Reference
1. Shi, Y. (2009) Serine/threonine phosphatases: mechanism through structure. Cell, 139, 468-484. PMID: 19879837


There are 3 genes.  Reviewed (3 or Unreviewed (0

No.StatusEKPD IDGene IDGene Name
1
EPS-HOS-00135
ENSG00000120910
CALNA3, CNA3; PPP3CC
2
EPS-HOS-00133
ENSG00000138814
CALNA, CNA; PPP3CA
3
EPS-HOS-00134
ENSG00000107758
PPP3CB; CALNA2, CALNB, CNA2