Latimeria chalumnae      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusEKPD IDGene IDGene Name
1
EKS-LAC-00406
ENSLACG00000002552
MAP3K4
2
EKS-LAC-00405
ENSLACG00000015267
MAP3K6
3
EKS-LAC-00407
ENSLACG00000007337
MAP3K1
4
EKS-LAC-00400
ENSLACG00000011038
MAP3K15
5
EKS-LAC-00401
ENSLACG00000000172
MAP3K5
6
EKS-LAC-00404
ENSLACG00000016123
7
EKS-LAC-00402
ENSLACG00000012374
MAP3K3
8
EKS-LAC-00403
ENSLACG00000001238
MAP3K2