Homo sapiens      STE      STE7

※ STE7 family introduction

    STE7 (MAP2K, MEK) kinases participate in the MAPK signaling cascades, STE7s are activated by STE11 and subsequent mediate the phosphorylation of MAPK kinases. STE7 are typical dual-specificity kinases and can phosphorylate the conserved TxY motif on MAPK. STE7 can further be classified into five subclasses: MEK1, MEK3, MEK4, MEK5 and MEK7 (1).

Reference
1. Wikinome Annotation:   Kinase Family STE7


There are 7 genes.  Reviewed (7 or Unreviewed (0

No.StatusEKPD IDGene IDGene Name
1
EKS-HOS-00235
ENSG00000126934
MAP2K2; MEK2, MKK2, PRKMK2
2
EKS-HOS-00238
ENSG00000137764
MEK5, MKK5, PRKMK5; MAP2K5
3
EKS-HOS-00237
ENSG00000076984
MAP2K7; JNKK2, MEK7, MKK7, PRKMK7, SKK4
4
EKS-HOS-00233
ENSG00000108984
MEK6, MKK6, PRKMK6, SKK3; MAP2K6
5
EKS-HOS-00236
ENSG00000034152
MEK3, MKK3, PRKMK3, SKK2; MAP2K3
6
EKS-HOS-00234
ENSG00000169032
MAP2K1; MEK1, PRKMK1
7
EKS-HOS-00232
ENSG00000065559
MAP2K4; JNKK1, MEK4, MKK4, PRKMK4, SEK1, SERK1, SKK1