※ RSK family introduction

    RSK kinase is part of the mammalian target of rapamycin (mTOR) pathway, which is a key regulator of cell growth via the regulation of protein synthesis. Both S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4EBP-1) are key mTOR effectors of cell growth. S6 kinase specifically phosphorylate ribosomal protein S6 in response to insulin or several classes of mitogens. S6 kinase is activated by Serine/Threonine phosphorylation and protein kinase C, and is inactivated by type 2A phosphatase. S6 kinase interacts with PPP1R9A/neurabin-1 (1).

Reference

1. InterPro Annotation: Ribosomal protein S6 kinase

  Reviewed (0)  or Unreviewed (6) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-ANC-00151	ENSACAG00000009878	RPS6KA5
2		EKS-ANC-00150	ENSACAG00000014143
3		EKS-ANC-00152	ENSACAG00000023067
4		EKS-ANC-00149	ENSACAG00000008242	RPS6KB2
5		EKS-ANC-00147	ENSACAG00000012681	RPS6KA3
6		EKS-ANC-00148	ENSACAG00000012931	RPS6KB1