※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (12) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-ICT-00447	ENSSTOG00000001819	MAPK10
2		EKS-ICT-00440	ENSSTOG00000012617	MAPK8
3		EKS-ICT-00445	ENSSTOG00000024211	MAPK15
4		EKS-ICT-00448	ENSSTOG00000002755	MAPK9
5		EKS-ICT-00450	ENSSTOG00000007526	NLK
6		EKS-ICT-00439	ENSSTOG00000015274	MAPK11
7		EKS-ICT-00449	ENSSTOG00000008218
8		EKS-ICT-00446	ENSSTOG00000022822	MAPK4
9		EKS-ICT-00444	ENSSTOG00000014791	MAPK1
10		EKS-ICT-00443	ENSSTOG00000000446	MAPK7
11		EKS-ICT-00442	ENSSTOG00000025085	MAPK13
12		EKS-ICT-00441	ENSSTOG00000000878	MAPK3