※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (17) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-ORL-00534	ENSORLG00000005162	MAPK9
2		EKS-ORL-00543	ENSORLG00000004822	MAPK4
3		EKS-ORL-00536	ENSORLG00000000393	MAPK13
4		EKS-ORL-00529	ENSORLG00000011993	MAPK3
5		EKS-ORL-00540	ENSORLG00000000204
6		EKS-ORL-00538	ENSORLG00000012626	MAPK15
7		EKS-ORL-00539	ENSORLG00000016122	MAPK14 (2 of 2)
8		EKS-ORL-00530	ENSORLG00000016296	MAPK12 (2 of 2)
9		EKS-ORL-00542	ENSORLG00000008944	MAPK11
10		EKS-ORL-00531	ENSORLG00000008884	MAPK8 (2 of 2)
11		EKS-ORL-00541	ENSORLG00000003082	MAPK6
12		EKS-ORL-00532	ENSORLG00000009012	MAPK12 (1 of 2)
13		EKS-ORL-00537	ENSORLG00000015084	NLK
14		EKS-ORL-00533	ENSORLG00000002370	MAPK8 (1 of 2)
15		EKS-ORL-00528	ENSORLG00000006477	MAPK14 (1 of 2)
16		EKS-ORL-00544	ENSORLG00000018802
17		EKS-ORL-00535	ENSORLG00000006580	MAPK7