Cavia porcellus      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusEKPD IDGene IDGene Name
1
EKS-CAP-00420
ENSCPOG00000012359
MAP3K6
2
EKS-CAP-00421
ENSCPOG00000013392
MAP3K4
3
EKS-CAP-00419
ENSCPOG00000002905
MAP3K2
4
EKS-CAP-00423
ENSCPOG00000015017
MAP3K1
5
EKS-CAP-00417
ENSCPOG00000022367
MAP3K3
6
EKS-CAP-00418
ENSCPOG00000004244
MAP3K5
7
EKS-CAP-00422
ENSCPOG00000004758
YSK4; MAP3K19