Gorilla gorilla      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusEKPD IDGene IDGene Name
1
EKS-GOG-00380
ENSGGOG00000004601
MAP3K2
2
EKS-GOG-00384
ENSGGOG00000015494
MAP3K5
3
EKS-GOG-00378
ENSGGOG00000004086
MAP3K3
4
EKS-GOG-00381
ENSGGOG00000008360
MAP3K4
5
EKS-GOG-00379
ENSGGOG00000008317
MAP3K15
6
EKS-GOG-00383
ENSGGOG00000014603
MAP3K1
7
EKS-GOG-00382
ENSGGOG00000014556
YSK4; MAP3K19