Monodelphis domestica      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusEKPD IDGene IDGene Name
1
EKS-MOD-00380
ENSMODG00000000785
YSK4; MAP3K19
2
EKS-MOD-00376
ENSMODG00000017436
MAP7
3
EKS-MOD-00378
ENSMODG00000014479
MAP3K6
4
EKS-MOD-00375
ENSMODG00000018690
MAP3K2
5
EKS-MOD-00379
ENSMODG00000006594
MAP3K4
6
EKS-MOD-00374
ENSMODG00000009983
MAP3K3
7
EKS-MOD-00377
ENSMODG00000009020
MAP3K15
8
EKS-MOD-00381
ENSMODG00000019524
MAP3K1