Myotis lucifugus      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusEKPD IDGene IDGene Name
1
EKS-MYL-00387
ENSMLUG00000001811
MAP3K6
2
EKS-MYL-00384
ENSMLUG00000011582
MAP3K3
3
EKS-MYL-00391
ENSMLUG00000011693
MAP3K1
4
EKS-MYL-00389
ENSMLUG00000016142
YSK4
5
EKS-MYL-00385
ENSMLUG00000023929
MAP3K2
6
EKS-MYL-00390
ENSMLUG00000012936
MAP3K15
7
EKS-MYL-00386
ENSMLUG00000007043
MAP3K5
8
EKS-MYL-00388
ENSMLUG00000014478
MAP3K4