Nomascus leucogenys      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusEKPD IDGene IDGene Name
1
EKS-NOL-00357
ENSNLEG00000008465
YSK4
2
EKS-NOL-00354
ENSNLEG00000004422
MAP3K3
3
EKS-NOL-00355
ENSNLEG00000014849
MAP3K5
4
EKS-NOL-00356
ENSNLEG00000015690
MAP3K2
5
EKS-NOL-00358
ENSNLEG00000002250
MAP3K1
6
EKS-NOL-00359
ENSNLEG00000009849
MAP3K15