Otolemur garnettii      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusEKPD IDGene IDGene Name
1
EKS-OTG-00390
ENSOGAG00000000556
MAP3K5
2
EKS-OTG-00393
ENSOGAG00000004556
MAP3K4
3
EKS-OTG-00389
ENSOGAG00000009109
MAP3K2
4
EKS-OTG-00394
ENSOGAG00000016799
YSK4; MAP3K19
5
EKS-OTG-00388
ENSOGAG00000006861
MAP3K3
6
EKS-OTG-00391
ENSOGAG00000002467
MAP3K15
7
EKS-OTG-00395
ENSOGAG00000002694
MAP3K1; B4USZ3_OTOGA
8
EKS-OTG-00392
ENSOGAG00000015094
MAP3K6