Sus scrofa      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusEKPD IDGene IDGene Name
1
EKS-SUS-00343
ENSSSCG00000015696
YSK4
2
EKS-SUS-00341
ENSSSCG00000004034
LOC100518100; MAP3K4
3
EKS-SUS-00345
ENSSSCG00000026041
MAP3K5
4
EKS-SUS-00339
ENSSSCG00000030354
MAP3K2
5
EKS-SUS-00338
ENSSSCG00000024813
MAP3K3
6
EKS-SUS-00340
ENSSSCG00000020735
MAP3K15
7
EKS-SUS-00344
ENSSSCG00000016918
MAP3K1
8
EKS-SUS-00342
ENSSSCG00000003573
MAP3K6