Homo sapiens      TK      Lmr

※ Lmr family introduction

    Lmr (Lemur tyrosine kinase) belong to tyrosine kinase family (1). Three members have been found in human genome. LMTK1, also known as AATK, is an apoptosis-associated tyrosine kinase; it contains an N-terminal tyrosine kinase domain and a C-terminal proline-rich domain. LMTK1 is required for induction of growth arrest or apoptosis of myeloid precursor cells. LMTK2 is thought to mediate the phosphorylation of PPP1C. Function and regulation LMTK3 remain further understood (2).

Reference
1. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002) The protein kinase complement of the human genome. Science, 298, 1912-1934. PMID: 12471243
2. Wikipedia annotation:    AATK


There are 3 genes.  Reviewed (3 or Unreviewed (0

No.StatusEKPD IDGene IDGene Name
1
EKS-HOS-00370
ENSG00000164715
LMTK2; AATYK2, BREK, KIAA1079, KPI2, LMR2
2
EKS-HOS-00368
ENSG00000142235
KIAA1883, TYKLM3; LMTK3
3
EKS-HOS-00369
ENSG00000181409
AATYK, KIAA0641, LMR1, LMTK1; AATK