※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (19) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-GAA-00567	ENSGACG00000018076	MAPK9
2		EKS-GAA-00571	ENSGACG00000014837
3		EKS-GAA-00558	ENSGACG00000014421	MAPK1
4		EKS-GAA-00569	ENSGACG00000019108	MAPK12 (1 of 2)
5		EKS-GAA-00559	ENSGACG00000019107	MAPK11
6		EKS-GAA-00572	ENSGACG00000015004	MAPK6
7		EKS-GAA-00568	ENSGACG00000003777
8		EKS-GAA-00574	ENSGACG00000007292	MAPK4
9		EKS-GAA-00563	ENSGACG00000007039	MAPK8 (2 of 2)
10		EKS-GAA-00566	ENSGACG00000007803	MAPK7
11		EKS-GAA-00556	ENSGACG00000007676	MAPK14 (1 of 2)
12		EKS-GAA-00561	ENSGACG00000004911	MAPK13
13		EKS-GAA-00573	ENSGACG00000004996	NLK
14		EKS-GAA-00564	ENSGACG00000016396	MAPK10
15		EKS-GAA-00557	ENSGACG00000008157	MAPK14 (2 of 2)
16		EKS-GAA-00560	ENSGACG00000013390	MAPK12 (2 of 2)
17		EKS-GAA-00565	ENSGACG00000013102	MAPK3
18		EKS-GAA-00562	ENSGACG00000005706	MAPK8 (1 of 2)
19		EKS-GAA-00570	ENSGACG00000005266	MAPK15