Takifugu rubripes      CMGC      MAPK

※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase


There are 18 genes.  Reviewed (0 or Unreviewed (18

No.StatusEKPD IDGene IDGene Name
1
EKS-TAR-00576
ENSTRUG00000013056
MAPK10
2
EKS-TAR-00584
ENSTRUG00000006607
nlk; Tru.1854
3
EKS-TAR-00587
ENSTRUG00000012974
MAPK4
4
EKS-TAR-00579
ENSTRUG00000012931
MAPK8 (2 of 2)
5
EKS-TAR-00574
ENSTRUG00000015300
MAPK1
6
EKS-TAR-00575
ENSTRUG00000005120
MAPK12 (1 of 2)
7
EKS-TAR-00571
ENSTRUG00000005697
MAPK3
8
EKS-TAR-00581
ENSTRUG00000000280
MAPK9
9
EKS-TAR-00583
ENSTRUG00000009284
MAPK15
10
EKS-TAR-00570
ENSTRUG00000016263
MAPK14 (2 of 2)
11
EKS-TAR-00585
ENSTRUG00000004328
12
EKS-TAR-00580
ENSTRUG00000010758
MAPK7
13
EKS-TAR-00582
ENSTRUG00000017128
MAPK8 (1 of 2)
14
EKS-TAR-00573
ENSTRUG00000008723
MAPK14 (1 of 2)
15
EKS-TAR-00572
ENSTRUG00000008739
MAPK11
16
EKS-TAR-00577
ENSTRUG00000008627
MAPK13
17
EKS-TAR-00578
ENSTRUG00000008589
MAPK12 (2 of 2)
18
EKS-TAR-00586
ENSTRUG00000017013
MAPK6