Pan troglodytes      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusEKPD IDGene IDGene Name
1
EKS-PAT-00368
ENSPTRG00000000404
MAP3K6; ENSG00000142733
2
EKS-PAT-00371
ENSPTRG00000022605
MAP3K15
3
EKS-PAT-00366
ENSPTRG00000009518
LOC468286; ENSG00000198909; MAP3K3
4
EKS-PAT-00370
ENSPTRG00000016891
MAP3K1; ENSG00000095015
5
EKS-PAT-00367
ENSPTRG00000012427
ENSG00000169967; MAP3K2
6
EKS-PAT-00369
ENSPTRG00000012490
YSK4; ENSG00000176601