Sarcophilus harrisii      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusEKPD IDGene IDGene Name
1
EKS-SAH-00357
ENSSHAG00000014925
MAP3K15
2
EKS-SAH-00360
ENSSHAG00000004375
MAP3K4
3
EKS-SAH-00359
ENSSHAG00000012760
MAP3K5
4
EKS-SAH-00363
ENSSHAG00000000519
MAP3K6
5
EKS-SAH-00356
ENSSHAG00000011962
MAP3K3
6
EKS-SAH-00358
ENSSHAG00000006267
MAP3K2
7
EKS-SAH-00361
ENSSHAG00000015928
YSK4; MAP3K19
8
EKS-SAH-00362
ENSSHAG00000010967
MAP3K1