※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (15) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-ANC-00457	ENSACAG00000001922	MAPK6
2		EKS-ANC-00447	ENSACAG00000001919	MAPK12
3		EKS-ANC-00453	ENSACAG00000007736	MAPK7
4		EKS-ANC-00458	ENSACAG00000010066	MAPK4
5		EKS-ANC-00456	ENSACAG00000010300
6		EKS-ANC-00455	ENSACAG00000015583	NLK
7		EKS-ANC-00449	ENSACAG00000015056	MAPK3
8		EKS-ANC-00452	ENSACAG00000011361	MAPK8
9		EKS-ANC-00454	ENSACAG00000011795	MAPK10
10		EKS-ANC-00451	ENSACAG00000016677	MAPK9
11		EKS-ANC-00448	ENSACAG00000016916	MAPK13
12		EKS-ANC-00445	ENSACAG00000016966	MAPK14
13		EKS-ANC-00459	ENSACAG00000024096	MAPK15
14		EKS-ANC-00446	ENSACAG00000001806	MAPK11
15		EKS-ANC-00450	ENSACAG00000001402	MAPK1