※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (16) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-CAJ-00470	ENSCJAG00000013551	MAPK8
2		EKS-CAJ-00479	ENSCJAG00000031670	LOC100407752; MAPK15
3		EKS-CAJ-00478	ENSCJAG00000032244
4		EKS-CAJ-00476	ENSCJAG00000000962	MAPK6
5		EKS-CAJ-00468	ENSCJAG00000010293	LOC100387686; MAPK9
6		EKS-CAJ-00471	ENSCJAG00000003322	MAPK12; LOC100396967
7		EKS-CAJ-00465	ENSCJAG00000003282	MAPK11
8		EKS-CAJ-00466	ENSCJAG00000015743	MAPK1; LOC100400700
9		EKS-CAJ-00467	ENSCJAG00000015899	MAPK13
10		EKS-CAJ-00464	ENSCJAG00000015852	MAPK14
11		EKS-CAJ-00475	ENSCJAG00000033925
12		EKS-CAJ-00472	ENSCJAG00000006770	LOC100404815; MAPK3
13		EKS-CAJ-00477	ENSCJAG00000001974	MAPK4
14		EKS-CAJ-00474	ENSCJAG00000012490	NLK
15		EKS-CAJ-00473	ENSCJAG00000001277	MAPK7
16		EKS-CAJ-00469	ENSCJAG00000005621	MAPK10