※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (12) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-EQC-00459	ENSECAG00000023749	MAPK4
2		EKS-EQC-00449	ENSECAG00000014460	MAPK3
3		EKS-EQC-00450	ENSECAG00000014175	MAPK14
4		EKS-EQC-00454	ENSECAG00000010551	MAPK1
5		EKS-EQC-00457	ENSECAG00000010309	NLK
6		EKS-EQC-00453	ENSECAG00000008480	MAPK8
7		EKS-EQC-00458	ENSECAG00000008209	MAPK6
8		EKS-EQC-00455	ENSECAG00000017373	MAPK12
9		EKS-EQC-00451	ENSECAG00000017280	MAPK10
10		EKS-EQC-00452	ENSECAG00000021489	MAPK9
11		EKS-EQC-00448	ENSECAG00000004780	MAPK11
12		EKS-EQC-00456	ENSECAG00000013433	MAPK7