Gallus gallus      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusEKPD IDGene IDGene Name
1
EKS-GAG-00331
ENSGALG00000014718
MAP3K1
2
EKS-GAG-00327
ENSGALG00000013892
MAP3K5
3
EKS-GAG-00329
ENSGALG00000005884
RCJMB04_4j19
4
EKS-GAG-00330
ENSGALG00000020003
MAP3K4
5
EKS-GAG-00332
ENSGALG00000012210
YSK4
6
EKS-GAG-00328
ENSGALG00000011502
MAP3K2
7
EKS-GAG-00326
ENSGALG00000016426
MAP3K15
8
EKS-GAG-00325
ENSGALG00000000525
MAP3K3