Ictidomys tridecemlineatus      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusEKPD IDGene IDGene Name
1
EKS-ICT-00369
ENSSTOG00000002821
MAP3K4
2
EKS-ICT-00366
ENSSTOG00000011012
MAP3K2
3
EKS-ICT-00367
ENSSTOG00000027298
MAP3K15
4
EKS-ICT-00371
ENSSTOG00000007184
MAP3K1
5
EKS-ICT-00368
ENSSTOG00000014251
MAP3K6
6
EKS-ICT-00370
ENSSTOG00000022671
YSK4; MAP3K19
7
EKS-ICT-00365
ENSSTOG00000008864
MAP3K3
8
EKS-ICT-00372
ENSSTOG00000009007
MAP3K5