Pongo abelii      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusEKPD IDGene IDGene Name
1
EKS-POA-00378
ENSPPYG00000020172
MAP3K15
2
EKS-POA-00382
ENSPPYG00000001665
MAP3K6
3
EKS-POA-00383
ENSPPYG00000015478
MAP3K1
4
EKS-POA-00377
ENSPPYG00000008527
MAP3K3
5
EKS-POA-00380
ENSPPYG00000012768
MAP3K2
6
EKS-POA-00384
ENSPPYG00000012812
YSK4; MAP3K19
7
EKS-POA-00381
ENSPPYG00000017155
MAP3K4
8
EKS-POA-00379
ENSPPYG00000017034
MAP3K5