※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (13) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-NOL-00426	ENSNLEG00000008900	MAPK14
2		EKS-NOL-00418	ENSNLEG00000008913	MAPK13
3		EKS-NOL-00424	ENSNLEG00000008765	MAPK7
4		EKS-NOL-00429	ENSNLEG00000011809	MAPK4
5		EKS-NOL-00422	ENSNLEG00000015573	MAPK8
6		EKS-NOL-00425	ENSNLEG00000001789	NLK
7		EKS-NOL-00420	ENSNLEG00000001965	MAPK9
8		EKS-NOL-00427	ENSNLEG00000001983	MAPK3
9		EKS-NOL-00428	ENSNLEG00000006476	MAPK6
10		EKS-NOL-00430	ENSNLEG00000002132	MAPK15
11		EKS-NOL-00423	ENSNLEG00000000240	MAPK1
12		EKS-NOL-00419	ENSNLEG00000000606	MAPK12
13		EKS-NOL-00421	ENSNLEG00000009285	MAPK10