※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (15) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-OTG-00472	ENSOGAG00000008164	MAPK8
2		EKS-OTG-00473	ENSOGAG00000012021	MAPK7
3		EKS-OTG-00474	ENSOGAG00000009099	MAPK1
4		EKS-OTG-00471	ENSOGAG00000016875	MAPK9
5		EKS-OTG-00479	ENSOGAG00000016663	MAPK4
6		EKS-OTG-00477	ENSOGAG00000030786	MAPK6
7		EKS-OTG-00468	ENSOGAG00000014169	MAPK12
8		EKS-OTG-00467	ENSOGAG00000014172	MAPK11
9		EKS-OTG-00470	ENSOGAG00000014897	MAPK10
10		EKS-OTG-00476	ENSOGAG00000027991	MAPK15
11		EKS-OTG-00478	ENSOGAG00000027841	MAPK3
12		EKS-OTG-00480	ENSOGAG00000027734
13		EKS-OTG-00466	ENSOGAG00000002814	MAPK14
14		EKS-OTG-00469	ENSOGAG00000002816	MAPK13
15		EKS-OTG-00475	ENSOGAG00000003321	NLK