※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (13) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-POA-00453	ENSPPYG00000002246	MAPK8
2		EKS-POA-00456	ENSPPYG00000018946	MAPK15
3		EKS-POA-00451	ENSPPYG00000014907	MAPK10
4		EKS-POA-00449	ENSPPYG00000007239	MAPK3
5		EKS-POA-00458	ENSPPYG00000012013
6		EKS-POA-00455	ENSPPYG00000008082	NLK
7		EKS-POA-00448	ENSPPYG00000016539	MAPK14
8		EKS-POA-00450	ENSPPYG00000016540	MAPK13
9		EKS-POA-00452	ENSPPYG00000016135	MAPK9
10		EKS-POA-00454	ENSPPYG00000011980	MAPK12
11		EKS-POA-00460	ENSPPYG00000011981	MAPK11
12		EKS-POA-00459	ENSPPYG00000029701	MAPK1
13		EKS-POA-00457	ENSPPYG00000009161	MAPK4