※ MAPK family introduction

    MAPK (mitogen-activated protein kinase) are serine/threonine specific protein kinases belonging to CMGC kinase group. MAPKs play an important role in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. MAPKs are involved in regulation of a variety of cellular processes, including cell proliferation, gene expression, differentiation, mitosis, cell survival and cell apoptosis. Three subfamilys constitute MAPK family, extracellular-receptor kinases (ERK), the c-Jun N-terminal kinases/stress-activated protein kinases (JNK/SAPK) and p38 MAPKinases. MAPK signaling pathways are important in animals, fungi and plants. ERK1/2 pathway is best understood in animals, which is essential for cell proliferation and cell cycle. Fus3 pathway is also well studied in fungi, which is responsible for cell cycle and mating in responses to pheromone stimulation. MAPKs pathway in plants may response to osmotic shock, oxidative stress, cold and anti-pathogen responses (1).

Reference
1. Wikipedia Annotation:    Mitogen-activated protein kinase

  Reviewed (0)  or Unreviewed (15) 

No.	Status	EKPD ID	Gene ID	Gene Name
1		EKS-SAH-00438	ENSSHAG00000002851	MAPK15
2		EKS-SAH-00435	ENSSHAG00000007720	MAPK1
3		EKS-SAH-00431	ENSSHAG00000002029	MAPK10
4		EKS-SAH-00428	ENSSHAG00000001726	MAPK14
5		EKS-SAH-00436	ENSSHAG00000013583	MAPK7
6		EKS-SAH-00442	ENSSHAG00000008861
7		EKS-SAH-00441	ENSSHAG00000013029	MAPK4
8		EKS-SAH-00433	ENSSHAG00000017573	MAPK8
9		EKS-SAH-00440	ENSSHAG00000017091
10		EKS-SAH-00429	ENSSHAG00000005652	MAPK13
11		EKS-SAH-00432	ENSSHAG00000005542	MAPK9
12		EKS-SAH-00434	ENSSHAG00000009776	MAPK11
13		EKS-SAH-00439	ENSSHAG00000009604	MAPK12
14		EKS-SAH-00437	ENSSHAG00000011623	NLK
15		EKS-SAH-00430	ENSSHAG00000010907	MAPK3