Ailuropoda melanoleuca      STE      STE11

※ STE11 family introduction

    STE11 family kinases are mitogen-activated protein kinase kinase kinase. Eight kinases compose this family and act as an essential component of the MAP kinase signal transduction pathway. STE11 family contains some subfamilys. MAP3K1/2/3/5/6 appears to diverged from SC:STE11, SCBCK1, SP:MHK1 and SP:BR2. SC:STE11 plays an important role in mating and filamentation-invasion pathways, BCK1 is responsible for nutrient sensing and growth, MHK1 is involved in cell-wall integrity, BYR2 participate innutrient sensing and pheromone signaling. MAP3K1/2/3/5/6 also act as key molecules in the JNK pathway, inflammation and cell apoptosis (1).

Reference
1. Kinase Pathway Database:STE11 Family


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusEKPD IDGene IDGene Name
1
EKS-AIM-00365
ENSAMEG00000016364
YSK4; MAP3K19
2
EKS-AIM-00362
ENSAMEG00000016682
MAP3K15
3
EKS-AIM-00360
ENSAMEG00000016823
MAP3K2
4
EKS-AIM-00361
ENSAMEG00000010066
MAP3K5
5
EKS-AIM-00364
ENSAMEG00000010924
MAP3K6
6
EKS-AIM-00359
ENSAMEG00000003294
PANDA_013942; MAP3K3
7
EKS-AIM-00366
ENSAMEG00000003644
MAP3K1
8
EKS-AIM-00363
ENSAMEG00000015908
MAP3K4